# Is Industrial Processing the Real Problem With Seed Oils? | Layne Norton, Ph.D. ## Метаданные - **Канал:** Peter Attia - **YouTube:** https://www.youtube.com/watch?v=Tsqzx3L6UWs - **Дата:** 23.01.2026 - **Длительность:** 8:50 - **Просмотры:** 8,892 ## Описание Get An Introductory Guide to Longevity and my weekly newsletter here (free): https://bit.ly/4jPxTkO Watch the full episode: https://youtu.be/iB49uq-t1UM Become a member to receive exclusive content: https://bit.ly/4pEvzy3 This clip is from episode #380 ‒ The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D. In this clip, they discuss: - Seed Oils Require Industrial Processing – Producing seed oils involves heating, refining, and large-scale chemical or mechanical extraction steps - Processing Raises Concerns About Purity – The concern is that heating, reheating, and refinement could alter linoleic acid compared to a pure laboratory form - Hexane Is Used for Efficient Extraction – Hexane is a non-polar solvent that effectively dissolves oils and can later be removed due to its low boiling point - Hexane Is Removed During Processing – Steam is used to evaporate hexane from the oil, with temperatures far below those required for significant oxidation - Impractical Exposure Threshold – Calculations suggest consuming over 11,000 kg of oil at once would be required to reach even mild effects from hexane -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. 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So, let's consider something else though, which is — for me to get a bottle of corn oil or any of the other seed oils on your table, I have to do a lot of industrial processing. Yep. — I have to heat these things up. I have to refine these oils. — Um, I have to use industrial-grade solvents to extract them. Um, it seems very likely that both of those processes can contribute to the negative impact of them independent of what we might see if we were talking about something pure. Right? In other words, [snorts] everything we've talked about so far is assuming a pure form of linoleic acid. But what if I'm now saying, "Yeah, but I'm gonna heat, reheat, cool, you know, bastardize this molecule, and oh, by the way, I'm not going to be able to get all the hexane off this molecule, and I needed to use hexane to extract it, right? This is how we people, you know, we don't like to talk about it, but food processing is big. You know, it it's big industrial chemistry, — right? And what I would say is the actual processing of the seed oils removes oxidants and removes some impurities that are maybe negative. Um there are some things that do increase and we'll talk about that. But let's let's start with the hexane itself. So to get the oils out of these seeds, you need to either do mechanical or chemical extraction. Now I think most people would say, "Well, I'd rather have the mechanical extraction, right? Because less chemicals. " But it is much more costly. The yield is lower. Um, and economics is a thing. — Is that an opportunity? Can you go into a grocery store and choose to have, you know, safflower oil that was mechanically extracted versus chemically extracted? — I actually have no clue, but I would imagine there are probably places that do sell it. Um, you know, and — you just pay more for it, but — for sure. Um, so let's talk about why hexane is used. So they take these seeds, they wash them with hexane. Why hexane? Well, hexane is a non-polar solvent. And when you're dealing with oil, you know, polar solvents are much more popular because most things or most things that we try to get are polar. Most things like to interact with water. It makes sense based on our biology and our biochemistry. Oils are different. Oils you have to do very unique things to. Hexane is a non-polar solvent, so it will mix with these oils and it has a relatively low boiling point. So you can evaporate it off. Okay. So these seeds get washed with this hexane. It extracts the crude oil. So now you've got the oil mixed with hexane. Well, now they bubble steam vapor through the oil and that evaporates off the hexane. Now I will tell you that the steam and the temperature is pretty low. In order to really start getting oxidation of seed oils, it depends on the oil specifically, but most of them you got to be well over 200 degrees Celsius and you've got to do it for hours. So, as if we're talking about in like a large vat, right? I think I read like soybean oil, if you heat it at like 240 degrees Celsius for like 3 hours, you will start to get like a percent of the oil being oxidized. But even after like 5 hours, it's still pretty small percentage points of oxidation. And this process of removing the hexane is on the order of minutes or an hour, 90 minutes. Like it's a pretty short period of time. And hexane's boiling point is I believe it's 69 degrees Celsius. So you only got to heat it up to a point, you know, a little bit above that to start getting it off. Now, okay, can you get all of it off? Well, as we anybody who's had basic chemistry, you know that no compound you synthesize is 100% pure. I mean, you can get 99. 999%, but you always have residual atoms in there. molecules in there. So the question becomes all right how much hexane is in the end product and how much is required to cause harm. The hexane in the end product most of them are well under one part per million. In fact a lot of them have non-detectable levels of hexane which means there's probably some in there but the instruments we have to measure it simply aren't sensitive enough to pick that out. So the amount of hexane in these thing in these oils I believe uh the research paper I read was anywhere from 0. 05 to 0. 5 parts per million for most of these oils. ### [5:00](https://www.youtube.com/watch?v=Tsqzx3L6UWs&t=300s) Segment 2 (05:00 - 08:00) Hexane specifically the danger with hexane is not from ingestion. It's actually from inhalation. So people who have had, you know, toxicity from hexane, it's from inhaling it. When you actually look at how much you hexane you'd have to get to like I don't even know if they've I I tried to look up hexane poisoning cases where somebody died. It doesn't exist. There's a case where a guy drank like literally drank straight hexane and basically got a tummy ache. Um they've done rodent studies where they were able to get toxicity and death, but basically they had to just to get mild liver and neurotoxicity. It was 5,000 milligrams per kilogram of body weight. Now when we do human equivalent dosage, um that dosage becomes smaller. But let me just put it in perspective as a bottom line. I did the calculation on this. What you would need to consume from hexane to even have mild side effects, what you would need to consume is 11,340 kg of oil at one time. — Okay, but that's to die. How do we know? — No, that was for mild side effects. Okay. But how do we know that mild or that accumulation of hexane or some other industrial solvent couldn't be leading to a chronic process? We've just talked about how — all the diseases we care about whether it be neurodeenerative diseases which you know or cancer or cardiovascular disease. These things don't happen overnight. They don't happen in weeks, months, even years. Many times they happen in decades. Right? And so if we're talking about a lifetime exposure to these things, how do we know that that's not increasing our risk? — So what I'd say is when we talk about lifetime exposure from something like LDL, that's a relatively high concentration in our bloodstream and it's always present. You always have a baseline level of LDL, right? Um you don't really have baseline levels of hexane in your bloodstream. I don't think at least not to any appreciable level. And there is a process you know through your body where your body converts this to something innocuous and gets rid of it. Right? So really when it comes to things that don't what we call bioaccumulate the question is if we have some of this is it in an amount that can be cleared quickly enough to where there's not negative outcomes. And what I would say is, okay, the example I gave was the amount of oil you need to consume to possibly get mild side effects. If anybody wants to, okay, say, let's just say your body couldn't process this out. Who's drinking 11,000 kg of oil in their lifetime? I think probably almost no one. So, I just don't see the possibility for hexane having a negative outcome for people, especially when you consider that it's a very low concentration. It doesn't bioaccumulate and your body has a way to process it out. And the amounts that you get are incredibly [snorts] small from these seed oils. — Okay. Now let's consider the fact that about a hundred years ago less than 3% of total food availability was made up of linoleic acid. Um today that number is I mean it's probably closer to 10%. --- *Источник: https://ekstraktznaniy.ru/video/16093*