# We Are (Slowly) Curing Cancer | Lightning Round ## Метаданные - **Канал:** Joe Scott - **YouTube:** https://www.youtube.com/watch?v=W73PfyrIrGQ ## Содержание ### [0:00](https://www.youtube.com/watch?v=W73PfyrIrGQ) Segment 1 (00:00 - 05:00) You think maybe we could stop with this whole getting cancer thing? Just in the last few weeks, we lost Katherine O'Hara and James Vanderbeek and hundreds of other people, I'm sure, that weren't on TV, but they're important to someone. I hate cancer and I am not ashamed to say it. Pretty much everybody who is watching this video has had their lives affected by cancer in some way and it is famously hard to treat. But we've been chiseling away at this problem for years and survival rates have never been higher. But will we ever totally cure cancer? That's one of the questions in today's lightning round video. Hey there and welcome to this month's lightning round video. For those of you who aren't familiar, lightning round videos are where I take questions from Patreons and members who support at the solar system level and uh and I give little quick answers to them. Sometimes they're mildly researched, sometimes they're not very researched at all. And if you guys see anything that you like that you really want to see a big deep dive video on, absolutely shout it out in the comments. It could happen. We got a few to get through today. So, let's start with question number one. This is from I love Thorium, who I believe is a new supporter at this level. So, they asked, "Will we ever be able to find a way to prevent cancer or at least certain kinds of cancers? I know some people will prevent certain cancers via surgery, but will we ever be able to find a way to prevent it in a less invasive way? " Um, I covered something close to this in a recent uh lightning round video not too long ago. Maybe I do need to do a deep dive on this because there's a lot going on here and it's something I feel pretty uh pretty passionate about. And just to be a little pedantic um in the question you're asking about preventing cancers via surgery, um that is not a preventative treatment. That is a treatment that happens once you get cancer. Um so preventing cancers and treating cancers, those are kind of different things. But if the question is will we ever cure cancer? Um I'm going to play Joe Stradamus and I'm going to say yes. Actually I I do think it is something that we are going to beat. I'm not optimistic about a lot of things about the future but that I'm actually somewhat optimistic about. Part of the reason I feel that way is because we are already kind of on the way there. There are a handful of cancers that we do kind of have a cure for and even a vaccine. For example, there's a HPV vaccine that helps prevent people from getting HPV, which leads to cervical cancers. So, that is already kind of a cancer vaccine. But the big hotness when it comes to cancer uh prevention and cancer treatments right now is mRNA vaccines. There are a lot of companies working on actual vaccines, shots that you can take that would prevent you from getting cancer. I know for some people mRNA vaccines are controversial. Um I don't think they should be and I certainly a political thing. But um one of the things that I had said back when COVID happened and we started working on mRNA vaccine for COVID was that this big push to research the technology behind mRNA vaccines could lead to a cure for cancer and that seems to be happening. And also to get a little pedantic on myself here um when we talk about curing cancer, cancer is not one disease. Cancer is literally hundreds of different types of diseases. diseases that kind of work the same way in that it's basically a mutation of your own body's cells that grows out of control and then winds up taking over and destroying organs and whatnot. But that's what makes it so hard to treat is because it is literally your body's own cells. So your immune system doesn't attack those cells because it recognizes them as your cells. But the thing about mRNA vaccines is that they can do what they call tumor specific antigens that apply specifically to the tumors. So they would basically get a biopsy of a tumor, take a look at its sequence ites DNA and whatnot, and then make an mRNA vaccine that brings out these tumor specific antigens that then triggers your immune system to attack that tumor cell and that tumor cell alone. Of course, that means we're basically talking about bespoke treatments. And that's what makes it so difficult. That's what makes it something that we never really been able to do before very effectively because it's not just like you can make a vaccine and send it out there and everybody can take it. It has to be made specifically for each person. But the technology for sequencing DNA, the technology for um crisper cast 9 and manipulating genetic material has gotten to the point now where it's kind of becoming feasible. And now with AI superpowering all the research, you know, I just did a video not too long ago where I was talking about alpha fold and how it's like figuring out all the different protein folding that can be done and all the different like uh classes of drugs that could be created off of that. Like I found this paper which is already about a year old, so it's probably progressed a lot ever since this came out. But I'll share this down in the comments. What I wanted to pull up though, this kind of talks about how mRNA vaccines work and whatnot, but take a look down here. Look, these are all the clinical trials that were going on at least as of last year of u of mRNA vaccines, mRNA treatments for cancers. ### [5:00](https://www.youtube.com/watch?v=W73PfyrIrGQ&t=300s) Segment 2 (05:00 - 10:00) Um, look how many of these there are. There's so many going on. It just keeps going. Still going. So, throughout this article, they're talking about the different types of cancers that can be treated. Tumor cancers, blood cancers, the different areas of the body that they focus on. But a few standout lines right here. It says extensive research and clinical trials has shown that these vaccines can stimulate robust immune responses and target specific cancer antigens leading to improved patient outcomes. It says mRNA vaccines have been shown to enhance the e efficacy of traditional treatments and provide new therapeutic options for cancers ranging from prostate to breast cancer and more challenging types such as pancreatic liver and brain cancers. I was talking about the tumor specific antigens a second ago. It speaks to that here. A key advancement in mRNA cancer vaccines is their ability to encode tumor specific antigens allowing the immune system to precisely recognize and attack cancer cells. It's saying here that colorectal cancer melanomas are some are diseases that respond really well to this. And it says here that uh this advancement could soon usher in new approaches to personalized cancer vaccines potentially improving outcomes for patients with melanoma and beyond. Now there are still some challenges. Um the downside of the immune system antigen style uh cancer vaccines is that if it doesn't work appropriately and winds up tagging your body's cells with that tumor specific antigen, then it kind of can turn into your body attacking itself. You can develop an autoimmune disease. You can get what they call a cytoine storm. That was something that we saw in COVID quite a bit. They're also still working on how to effectively um distribute the mRNA molecules. Uh there have been people talking about like putting them in different viruses and just let the virus do the thing and spread it around the body. Sometimes it's a little bit more complicated than that. They're working on different uh you know lipid uh sort of encapsulizations of these things to get them to the right cells at the right time. Anyway, that article is going to be down in the comments if you want to get all the details, but long story short, there's still some significant hurdles to overcome. But as you saw, there's a whole bunch of research going into this. There's a whole lot of money that's going into this. There was a big spurring of mRNA technology with COVID. And uh yeah, I think it's I think it's safe to say that we're going to be seeing probably the first Here's my here's Okay, here's my Jous prediction. I think there will be an FDA approved cancer vaccine in the next 5 years. And I think once that first one gets approved and becomes, you know, popular and useful, we're going to see a whole lot more of them. and there's going to be a whole flurry of them. I know I'm oversimplifying a lot here. It's a very complicated problem. Um, and I'm sure that the mRNA thing will run into some roadblocks that we don't even know about yet, but the research is going strong and we're making huge advancements. And like I said, there's a lot of things in the world that I'm not all that optimistic about. This one, I actually am. I do think that we are going to crack cancer someday. And it can't come fast enough because, and I mean this from my heart, cancer. All right, next up, Dan M asked, "What's the most unsung benefit of living in Dallas? " Uh, not being from Fort Worth. Damn, actually. No, Fort Worth is great. Fort Worth is actually pretty cool. Um, it's not unsung. Most people know about this, but the food here is actually really great. There's the Texas staples like your TexMax food, your barbecue. Um, it's very kind of Texas specific and it's not like anywhere else in the world. My wife and I are always saying if we ever moved out of Texas, that's what we've missed the most is the Mexican food. Surprisingly, Dallas just got their first um Michelin starred restaurant. I don't know what took so long, but yeah. There's also a surprisingly large like Asian and Indian community in the DFW area, which means that there's a lot of like diversity and uh types of food that you won't be able to find out in, you know, the small towns and stuff. Real estate prices are more reasonable here than you would find on the coasts. But I will say there's a reason for that. It's because there's no coast here. But if I were to pick one thing, I think I would pick just the fact that it's so centrally located. Um, I guess Chicago would have a similar thing, but like you know it when you want to talk to somebody on the west coast and you need east coast, there's only like a one or two hour difference. It's not like being on the west coast trying to talk to somebody in New York and you got to, you know, it's they're like 3 hours ahead of you. Also, that makes DFW a good hub for like airlines to just fly everywhere. It's kind of easy to get anywhere on by plane here. So, if you want an unsung benefit of living here, it would probably be that. People don't talk about that as much, but it's kind of nice to have like a c you be in a central location where you can like get to the places you want to go pretty easily. Real quick, shameless self-promotion, my film, my documentary, Oldest and Newest Places on Earth, is going to be screening in Boulder at the Scorpius Fest Film Festival on March 1st at 10:50 a. m. as part of their lineup. If you are anywhere near that area, um I'll put a link down below where you can go check it out. Come see it. I'll be ### [10:00](https://www.youtube.com/watch?v=W73PfyrIrGQ&t=600s) Segment 3 (10:00 - 15:00) there. Harrison asked, "Of all the videos you've done, what are some of the topics you still read up on? " Um, interesting. So, like a lot of my videos are stories, um, like stories from the past or, you know, mysteries and stuff like that. And there's not a whole lot to like keep up on because it's a story that's been told and there's not much to be added to. Um, I do stay up, uh, try to stay up on things like VR and like um, smart glasses just because there's a lot going on there. Um, y'all might remember I did the uh, Apple Vision Pro video. For the record, I almost never used that thing. I wish I used it more. I just haven't found as much utility for it. But I stand by what I said about it kind of proving out a technology and a new uh a new communication device because I mean something is going to take the place of the phone someday. This is not the end all beall of technology. There's going to be something else. And I think VR and smart glasses is probably the most likely for better and for worse. I don't know if that's a good thing or not. Um I still keep up with EV news even though I don't really talk about EVs as much anymore. Um, you know, it's still a topic I'm interested in and I still drive one. But I do tend to keep going back to like the Victorian age. I if I'm on YouTube and I'm, you know, doing whatever, if I run across a video about the Victorian age, I tend to go back to it. I just find that whole time period uh fascinating. And actually, I've got a video on the way that talks about that time period. So, I still dig into that quite a bit. Yeah. All right. Brian Bezwick asked, "Asking before the launch, assuming it will be between now and this video, how did the Artemis launch go? " Ryan Coburn asked, "Recently, Chad GBT confidently told me that Joe Biden, not Donald Trump, is the current president and doubled down when challenged. When asked why it didn't check the internet, the response was it had no internet access. " How concerned should we be about AI that is both wrong and certain and will this actually improve? Wrong and certain sounds like somebody else I know. That's somebody else being everyone. So, a lot of people who are a lot smarter than me have said that uh the current LLM architecture that we use for uh AI is limited and is never going to quite get to the AGI that we were promised and that something else is going to have to come along if we're ever going to get to that point. So, to ask if it'll ever get better, I mean, I think it will, but I definitely think it's going to be something that's not like LLMs that comes along uh that kind of disrupts the whole thing. Probably after we spend a trillion dollars on all these data centers, that's that should be fun. So, I actually don't use Chad GBT that much. And there's probably some people in the comments that are going to go in there and say that the whole no internet access thing might have something to do with the the level of Chad GBT that you're signed up for or something. I don't know. I'm sure somebody's going to like correct me in the comments on that. But whenever I do use Chad GBT, I use it sparingly to begin with. And whenever I do it, I always have to make sure that I get the sources. I ask it to give me sources to back up the things that it says cuz I'll never forget when it first came out and I u I you know, I was like, "Hey, what's this all about? " And I started trying to use it to help research. I used it once to help research a video and it gave me uh something that was very demonstrabably untrue. And I'm like, "Okay, well, I'm never going to trust this again. " I do think it's like a good thought partner to kind of help you sort through your ideas or to organize your thoughts and whatnot. Um, I think it's good for that. Using it as a tool, not to have it like write the stuff for you, but to kind of help you to write the stuff. The problem is that most people don't care about how accurate it is. It's just a timesaver. You could call them lazy if you want. They'll say that they're being more productive, but it's just um it's just a thing that they use to get the stuff done, and they really don't care how accurate it is. That honestly bothers me more than the chatbt itself being wrong is the number of people who just don't care whether or not it's wrong. Like I know there's a really strong anti- AI sentiment out there. Some of that has actually been turned on me at times because in the past I did use it to make some thumbnails. Those have all been removed by the way. So there's a very strong anti-AII sentiment. But what I'm seeing on social media is that most people, the normies, they don't care. They just think it's a fun little toy to make little cute pictures that they can put up on Facebook. There's a whole trend of AI photos going around Facebook recently, which frankly bothers me more than the people who get upset with me. Like, it bothers me more that more people aren't bothered by it than the people who are bothered by the little amount that I've used it. I just think it's a useful tool that should be used sparingly, with restraint, and with a lot of skepticism. And that skepticism needs to be directed toward the companies that make it as well. We got one more question to get to, but before we do, let's welcome the new channel members and Patreon supporters with the power of Zoey. Here we go. We got first up on the Patreon side, we got Rebecca Sparenberg, Chelsea Lou, Todd Odengard ### [15:00](https://www.youtube.com/watch?v=W73PfyrIrGQ&t=900s) Segment 4 (15:00 - 20:00) uh Sandra McLaren, Kelly Falenberg, I love Thorium, who asked a question earlier, uh Basher0521, Dark Hamster, Salvatore Canestra, uh Jodie Poochie, Ding Ding, sorry, Anthony Snyder, Yanvatic, uh Ashley Habitz, Ty McGee, and Nathan Coleman. And for members, we've got Helen Jensen, Jonathan Chver, Shaggy the God, Ko Lever, uh G Caldis 3141, Ernie Peterson, uh Jess Lance, Dr. Niels Rasmmanson, Terresa Cohen, Retro Game Bruise, Theramin, Electro, Jason Plant, Terraagal, JSB, and Robert Churchill. Thank you guys so much for signing up. And if you would like to join them, you can get a little thing next to your name down in the comments and stand out in front of everybody. Or just join a really awesome community over on Discord and whatnot. Uh, you can just go to patreon. com/anserswithjo or just click the join button for the membership down below. All right, last question goes to racezer humor singer who asked, "Will we ever discover why gravity is so weak compared to the other fundamental interactions in physics again in Joe Stradamus mode? Um, I have to say I hope so. I feel like a lot of our sci-fi visions that we want to see come true um kind of rely on the uh potential of us ever learning how to manipulate gravity. I'm talking about things like flying cars, warp speed, space transport, that kind of thing. Like if you were able to create a gravity well in front of your ship, or be able to flip gravity so that it's repulsive instead of attractive. Um, it feels like you'd be able to do those things, right? Gravity, honestly, gravity always trips me up. It's a very weird force. Um, and I like I get that it causes spaceime to curve, but like how? Like I found this video from a channel called Alpha Phoenix where he talks about how like gravity is basically just reference frames of spaceime accelerating toward uh toward Earth. Um looks like it's falling. It may not be exact, but my favorite way to think about this is literally to imagine falling reference frames anywhere. You can just pop a reference frame into existence at zero velocity and watch it fall. — He goes way in depth on gravity and how it works. I'll link to it down below. definitely worth a check out. And you're right, of the four fundamental forces, um, gravity is by far the weakest, even though it kind of works everything in our galaxy and universe. And we still don't know why. a lot of things about gravity, but trying to find those answers leads to a lot of uh interesting ideas. Things like gravitational particles hidden inside of extra dimensions that we can't see kind of stuff, which could explain dark matter as well. Anyway, wacky stuff. If the question though is like, will we ever figure it out? Time is long. Anything is possible. I hope that we do because I think that would give us the sci-fi future that we all want. So, it might be a fundamental particle we haven't found. It might be matter folded into hidden dimensions. It might be white holes adding density from black holes in other universes. It might be all of the above. Maybe there's a theory out there that we haven't discovered just yet that kind of combines all the different ideas in a way that just works. Like imagine if you applied that idea to an internet browser. It might look something like Opera. If you're a creature of habit and you've been using the same browser for a long time, I know I fall into that category. I might suggest you check out Opera. Opera is kind of like the ultimate internet productivity tool. It just does it all. I recently checked out Opera and I started testing it out, using it, and I've got to say it is quickly becoming my new daily driver. Let me tell you why. First of all, the tab islands. Like, whenever I share something from my browser in live streams or Zoom calls or whatever, I always get the comments about all my open tabs. And yeah, it's not uncommon for me to have more than 50 tabs open at a time. And it is a problem, especially when it takes 10 minutes to find the right tab I left open specifically so I could come back to it later. Well, on Opera, I have tab islands, so I can group tabs together by category, like research tabs or social media tabs or streaming tabs. This lets you group your tabs with an option to just expand and collapse them when needed. You can even color code them and name them however you like. There's also this cool split screen feature that lets you have up to four tabs open at once. So you can say compare different articles against each other or take notes in one tab on an article in another tab. It's super useful. All you have to do is just drag the tab down to split the screen and it automatically adjusts. It kind of feels like Opera makes it so you never have to leave the browser to do anything you need to do. Like I said, it does it all. Like on the sidebar here, you can put shortcuts to various tools like Google services, Gmail, Calendar, and whatnot. All those tabs that you keep open on your computer all the time, they can just live here. And they've also got a music player here that slides out. You can pick your favorite music player and then you can pop out a little floating player here to control the music while you get stuff done. And you can put that anywhere. It doesn't have to be in the browser. But my favorite is a guy who watches a lot of YouTube is the video pop out feature. Say you're watching a handsome guy on YouTube, but you also need to look some stuff up. Well, instead of having to create a whole new window, you can just pop out the video and it'll hover there on top while you move on to other ### [20:00](https://www.youtube.com/watch?v=W73PfyrIrGQ&t=1200s) Segment 5 (20:00 - 20:00) websites. freaking game changer. Seriously, if you've been using the same browser for a long time, you might be surprised how much you can do with Opera. It just makes a lot of sense. And the best part is it's free. So download Opera at the link down below in the description. Try it out for yourself. And thanks to Opera for supporting this video. All right, that's it for today. Uh thanks to all the people who asked the questions. I appreciate it. If you are new to this channel, um I'll put a little link up here. You can go check out some of my other videos. Most of my videos are deep dives on uh specific questions. And again, if any of these questions seem like something you'd like to see in a deep dive, let me know in the comments. It could happen. Please do like and share this video if you liked it. And if you didn't, just don't do anything. That's it for today. You guys go out there, have an eye opening rest of the week, stay safe, and I'll see you next Monday. Love you guys. Take care. --- *Источник: https://ekstraktznaniy.ru/video/42785*