Exerkines: how exercise supports brain health and longevity with neuroscientist Dr Lila Landowski
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Our brain shrinks by about 5% per decade after age 40. Physical exercise is key for brain health and longevity, but when I say exercise, I don't just mean cardio! Our bones and muscles also release factors during exercise ("exerkines" like osteocalcin, VEGF, IGF-1) which also support neuroplasticity, and your brain's ability to make new brain cells through a process called "neurogenesis."
Check out this great Lancet review if you want to find out more about exerkines and the brain: Tari A. et al 2025, The Lancet, 405, 1093-1118
🎥 Project100 podcast with Mark Bouris FT @LilaLandowski https://open.spotify.com/episode/5OKvN4XVbe6bxH1sbRoKEw