Why is hantavirus so deadly?

The virus comes in to the alveolar space. This can happen because the viruses are in the mouse droppings, urine, or saliva. And if they get stirred up because someone is sweeping or vacuuming and they're not wearing the appropriate mask and protection, they could inhale these viral particles. And then these viral particles will specifically infect endothelial cells. And because they're being inhaled, this is the vasculature that they infect, the pulmonary vasculature. And to make a long story short, which we'll go into, essentially what happens is that when they infect these endothelial cells, this infection can go on for days if it's not taken care of by the innate immune system, which includes interferon. We've talked about this before. What these viral particles do is it suppresses the body's ability to make interferon. That's why this thing goes on for such a long time. These symptoms can go on for days before the ultimate collapse occurs. — gram. com